Our PCAB-accredited pharmacists compound LDN in custom low doses prescribed by your provider — so your prescription reflects your biology, not a population average.
Low dose naltrexone — or LDN — is the same medication used at high doses to treat opioid and alcohol dependence, but prescribed at a fraction of those doses (typically 1.5–4.5 mg) for a very different purpose: modulating the immune system and central nervous system in ways that may help support patients with chronic autoimmune, inflammatory, and pain conditions.
LDN works differently at low doses than it does at the standard 50 mg FDA-approved dose. Research suggests that at low doses, naltrexone briefly blocks certain receptors in a way that signals the body to upregulate its own endorphins and modulate immune activity overnight.
Because commercial naltrexone isn't manufactured in 1.5 mg, 3 mg, or 4.5 mg doses, LDN has to be compounded. That's where a PCAB-accredited compounding pharmacy comes in — your provider writes the prescription at the dose that fits your protocol, and a pharmacist compounds it to match.
Patients often arrive at LDN after trying conventional options that haven't fit — a Hashimoto's patient still exhausted on Synthroid, a fibromyalgia patient cycling through pain medications, an autoimmune patient whose flare cycles aren't improving. LDN isn't a replacement for those treatments. Prescribed by your provider, it's a tool that may help support your body's own regulatory systems alongside the rest of your care.
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Magnolia Pharmacy has been compounding in the Houston metro since 2002. Our owner and lead pharmacist, Steve Hoffart, PharmD, was named PCCA's Compounding Pharmacist of the Year in 2022 — a national recognition for clinical excellence in personalized compounding.
Our pharmacists review every compound. When your provider sends an LDN prescription, our team checks the dose, the titration schedule, and the formulation against your protocol — and flags anything worth a conversation before we compound it.
We compound LDN in the specific dose your provider prescribes — not a rounded approximation. That matters at 1.5, 3, and 4.5 mg, where small differences in dose meaningfully affect how patients respond.
Patient, physician, pharmacist — working together. Your provider prescribes the protocol. We compound and counsel. You communicate how you're responding. When all three are on the same page, dosing adjustments happen faster.
LDN is a prescription medication. Your provider evaluates whether LDN fits your clinical picture and writes the starting dose — typically 1.5 mg, titrating up over several weeks.
We coordinate with your provider's office on dosing, timing, and titration schedule. If we see anything worth confirming, we call before we compound.
LDN is prepared in our compounding lab at the exact dose your provider prescribed. Typical forms include capsules and liquid; your provider specifies which fits.
Pick up at our Magnolia, TX pharmacy or have your prescription shipped within Texas. Refills coordinate through our team.
Ready to talk with a pharmacist about whether compounded LDN fits your situation?
Schedule a ConsultationMagnolia is a PCAB-accredited 503A compounding pharmacy in the Houston metro. Our pharmacists compound LDN in capsule and liquid formulations at custom doses — typically 1.5, 3, and 4.5 mg, and anything in between your protocol specifies.
We coordinate directly with your office on titration schedules, refills, and patient questions. Typical turnaround for LDN compounds is 2–3 business days*. For rush needs, our team is reachable directly.
* STEVE REVIEW (F1): confirm canonical turnaround days for LDN compounds.
Pharmacist-curated, not algorithm-curated. Supportive — not a replacement for the compound itself. Each is clinically selected by our team and should be reviewed with your provider.
May help support healthy inflammatory balance, often used alongside autoimmune protocols.
May help support immune regulation and bone health.
May help support calm, restful sleep — which matters on LDN, taken at bedtime.
May help support energy metabolism and methylation pathways taxed under chronic stress.
Subscribe to any supplement and save on every recurring order. Cancel or pause anytime. (Subscription applies to supplements only; compounded LDN refills are coordinated through your provider.)
Low dose naltrexone is naltrexone prescribed at 1.5–4.5 mg — a fraction of the FDA-approved 50 mg dose used for opioid and alcohol dependence. At these low doses, research suggests it may help support immune regulation and endorphin signaling in patients with chronic autoimmune, inflammatory, and pain conditions. Because commercial naltrexone isn't manufactured in these low doses, LDN has to be compounded at a pharmacy like Magnolia.
Yes — in dose and purpose, not in the underlying medication. Standard naltrexone is 50 mg and is used for opioid and alcohol dependence. Compounded LDN is 1.5–4.5 mg and is prescribed off-label by your provider for chronic conditions where low-dose immune modulation may be supportive. Both use the same active ingredient; the dose changes everything about how it's used.
Most patients report noticing changes over several weeks, though individual timelines vary based on your condition, dose, and titration. LDN is typically titrated slowly over 4–6 weeks, and the full effect may take 2–3 months. Your provider and our pharmacists can help you navigate dosing adjustments based on how you respond.
Some patients experience vivid dreams, sleep disturbances, headaches, or GI symptoms, particularly in the first 1–2 weeks. These are typically transient. Report persistent side effects to your provider.
Most insurance plans don't cover compounded medications, and LDN is almost always out-of-pocket. Cost varies by formulation and supply. Our team can walk you through pricing when your provider sends the prescription.
You don't need to come in for the consultation — your provider writes the prescription, and our team coordinates directly with their office. You can pick up at our Magnolia, TX pharmacy or have your prescription shipped within Texas.
Our standard LDN formulations are capsules and liquid — your provider specifies which fits your protocol. Capsules are most common; liquid formulations are often used when a provider needs more granular titration.
Magnolia's patient community is where patients, our pharmacy team, and curated education meet — for pharmacist Q&A, education on compounds like LDN, and ongoing support for navigating chronic conditions. Free and paid tiers available.
Join the CommunityIf you've been told your labs look fine but you still feel off, a pharmacist consultation is where the next step begins.
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